Kisspeptin-10 [Peptide]

Description

Kisspeptin-10 [Peptide]

The product is only intended for laboratory research use and not for human consumption. 

Available quantities:

• 5 mg
• 10 mg

Product Information 

Product name	Kisspeptin-10
Peptide purity (HPLC)	98-99%
Molecular Formula	C₆₃H₈₃N₁₇O₁₄
Molecular Weight	1302.4 g/mol
Synonyms	Metastin (45–54); KP-10; KISS1; KP10 Peptide
CAS	374675-21-5
IUPAC	DL-tyrosyl-DL-asparagyl-DL-tryptophyl-DL-asparagyl-DL-seryl-DL-phenylalanyl-glycyl-DL-leucyl-DL-arginyl-DL-phenylalaninamide
Source	Synthetic
Form	Powder
Shelf Life	Up to 2 years in powder form under recommended conditions

Molecular Sequence of Kisspeptin-10 Peptide 

H–Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Phe–NH₂ ®

• H– indicates the free amine group at the N-terminus. 
• –NH₂ indicates C-terminal amidation (common for Kisspeptin peptides to enhance stability). 
• Kisspeptin-10 is the biologically active decapeptide fragment of the longer Kisspeptin-54.® 
• In research models, it acts as a potent agonist of the GPR54 (KISS1R) receptor and plays a vital role in regulating GnRH (gonadotropin-releasing hormone) secretion and reproductive function. 

Handling and Storage of Kisspeptin-10 Peptide

The peptides should be stored in a cool and dry place to maximize their stability. Reconstituted liquid Kisspeptin-10 should be stored at 2–8 °C for short-term storage.®

For Kisspeptin-10 lyophilized peptides, it is recommended to store them in the refrigerator between 2°C and 8°C (36°F–46°F) in an air-sealed container. ®

Lab user exposure	Redissolving	Choice of container and precautions
Wear laboratory coats, nitrile gloves, and eye protection.  Avoid prolonged or repeated exposure and avoid inhalation. Avoid contact with eyes or skin.  The product is non-hazardous for lab-to-lab or air transportation. Handle inside standard laboratory containment.	Can be reconstituted in sterile distilled water or suitable buffer solutions.  A small amount of DMSO or 0.1% TFA may be used to test or improve solubility.  Mix gently, avoid high-temperature heating.	Low-binding sterile polypropylene to prevent absorption.  Borosilicate glass vials to prevent absorption in the glass walls.   Avoid polystyrene and lab plastic containers. Use amber vials or opaque containers.

Overview of the Kisspeptin-10 Peptide

Kisspeptin-10 is a synthetic decapeptide. It has the potential to mimic the bioactive fragment of the endogenous peptide encoded by the KISS1 gene. In experimental models, the peptide may influence neuroendocrine signaling, particularly in regulating the hypothalamic-pituitary-gonadal (HPG) axis. ®

Working Mechanism of Kisspeptin-10 Peptide

Laboratory research suggests that by binding to the receptor KISS1R (also known as GPR54) on GnRH neurons in the hypothalamus, Kisspeptin-10 stimulates the release of gonadotropin-releasing hormone (GnRH). 

The hormone, in turn, promotes the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. These hormones are essential for reproductive function and sex steroid production, including testosterone in laboratory models. ®

 

Additionally, preliminary studies suggest its impact on memory and learning, mood regulation, and metabolic pathways in genetic and chronic diseases. ®

 

Besides potential working mechanisms, the peptide also has some side effects under laboratory settings.

• Mood fluctuations 
• Nausea 
• Headache

TFA Salt Form 

Kisspeptin-10 is provided in its TFA salt form. Residual trifluoroacetate content is typically up to 10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA.

Disclaimer

Kisspeptin-10 peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.

For queries, complaints, or support, please contact support@rcdbio.co.