MIF-1 [Peptide]

Description

What is MIF-1?

Melanocyte-Inhibiting Factor-1 (MIF-1) is a naturally occurring tripeptide. It is also known as Pro-leu-Gly-NH2.  MIF-1 is derived from the breakdown of oxytocin, a bonding hormone. Researchers study MIF-1 for its neuromodulatory effects in experimental settings. 

MIF-1 is also believed to influence mood, motor function, and cognitive processes in research settings. Researchers find this compound very interesting because it acts as a positive allosteric modulator of dopamine receptors, particularly D2 and D3. 

Additionally, it works as an opioid receptor antagonist and enhances melatonin activity. All these factors make MIF-1 a compelling subject for ongoing research. 

Chemical Properties

PubChem CID	137700208
Molecular Formula	C15H25F3N4O5
Molecular Weight	398.38 g/mol
Synonyms	MIF-1 (TFA) MIF-1 TFA 35240-69-8 (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid HY-107663A
IUPAC	L-prolyl-L-leucyl-glycinamide trifluoroacetic acid

 

How Does MIF-1 Work?

MIF-1 (Melanocyte-Inhibiting Factor-1) works by modulating several neurochemical pathways in the brain. Here is a quick overview of how it works in research subjects:

• Enhances Dopamine Signaling: 

Researchers have observed that MIF-1 may improve dopamine receptors (especially D₂ and D₄) respond to dopamine. The process may support mood, motivation, and cognitive function in research models.

• Blocks Opioid Receptors: 

MIF-1 has been shown to act as a mild opioid receptor antagonist. This means it may potentially reduce the effects of natural or synthetic opioids. It may help balance emotional responses and possibly reduce dependence-related behaviors in experimental settings.

• Boosts Melatonin Activity: 

MIF-1 increases the effects of melatonin, a hormone that regulates sleep and circadian rhythms. This may contribute to its calming, neuroprotective, and mood-stabilizing effects observed in research subjects.

What are the Potential Benefits of MIF-1?

Researchers have observed the following benefits of MIF-1 in different research settings. 

• Exhibits antidepressant-like effects in research subjects
• Enhances dopaminergic neurotransmission in research subjects
• Demonstrates neuroprotective properties in research subjects
• Modulates opioid receptor antagonism in research subjects
• Improves motor function and coordination in research subjects

What are the Potential Side Effects of MIF-1? 

Though long-term research is needed to understand the safety profile of MIF-1. So far, researchers have observed these potential side effects.

• Potential for mild neurotoxicity in research settings
• Possible altered neurotransmitter balance in research settings
• Risk of motor hyperactivity or dyskinesia in research settings
• Occasional changes in blood pressure in research settings
• Minor gastrointestinal disturbances in research settings

Where to Buy MIF-1? 

The best place to buy MIF-1 is RCDbio for a lot of reasons. Our online shop provides you with genuine quality research compounds. You can order the MIF-1 without any hassle because we offer a third-party-tested MIF-1. Moreover, we provide a certificate of analysis (COA) with MIF-1 for purity and consistency. Above all, we give you secure payment options along with fast shipping. 

FAQs

1. What is the shelf life of MIF-1 in research settings?

The MIF-1 has a shelf life of about 1 to 2 years when stored properly.

2. What is the half-life of MIF-1 in research settings?

The plasma half-life of MIF-1 is approximately 2 to 5 minutes in vivo.

3. Is MIF-1 stable in research settings?

MIF-1 is relatively stable when stored lyophilized. However, it can degrade quickly in solution without proper conditions.

4. Can MIF-1 degrade in research settings?

Yes, MIF-1 can degrade if exposed to high temperatures, moisture, or improper pH levels.

5. What is the best temperature to store MIF-1 in research settings?

MIF-1 should be stored at -20°C or lower to maintain stability and potency over time.

Disclaimer:

MIF-1  is exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, prevent, or cure any disease. 

The Food and Drug Administration has not evaluated the statements on our website. Researchers must comply with all applicable local laws and regulations. By purchasing, you agree to our Terms and Conditions. In addition, RCDbio reserves the right to refuse sales to unauthorized individuals. 

For queries, complaints, or support, contact support@rcdbio.co.