Retatrutide [Peptide]

Description

Retatrutide [Peptide]

The product is only intended for laboratory use and not for human consumption. 

Available quantities:

• 5 mg
• 8 mg
• 10 mg
• 12 mg

Product Information 

Pubchem CID	171390338
Peptide purity (HPLC)	98-99%
Molecular Formula	C221H342N46O68 ®
Molecular Weight	4731 g/mol
Synonyms	Retatrutide, 2381089-83-2, orb1981169, EX-A7826E, GTPL13769 ®
IUPAC	LY-3437943
CAS	2381089-83-2
Source	Synthetic
Form	Powder
Shelf Life	12-14 months under recommended conditions

Molecular Sequence of Retatrutide Peptide 

Tyr–Aib–Gln–Gly–Thr–Phe–Thr–Ser–Asp–Tyr–Ser–Ile–Aib–Leu–Asp–Lys{C20-diacid–γ-Glu–AEEA}–Ala–Gln–Aib–Ala–Phe–Ile–Glu–Tyr–Leu–Leu–Glu–Gly–Gly–Pro–Ser–Ser–Gly–Ala–Pro–Pro–Pro–Ser-NH₂

• Aib: α-Aminoisobutyric Acid
• γ-Glu: γ-Glutamic Acid
• AEEA: Aminoethoxyethoxyacetic Acid
• C20-diacid fatty chain attached to the ε-amine of Lysine

Recommended Handling and Storage 

The compound should be stored in a cool and dry place to maximize its stability. For better storage, it is recommended to keep the Retatrutide  Lyophilized peptides refrigerated between 2°C and 8°C (36°F–46°F) in an air-sealed container. ®

Lab user exposure: 

• Avoid prolonged or repeated exposure.
• Avoid inhalation.
• Avoid contact with eyes or skin.
• The product is non-hazardous for lab-to-lab or air transportation.
• Handle inside standard laboratory containment.
• Use gloves, a lab coat, and protective eyewear.

Redissolving:

• Can be reconstituted in sterile distilled water or suitable buffer solutions.
• A small amount of DMSO or 0.1% TFA may be used to test or improve solubility.
• Mix gently, avoid high-temperature heating. 

Choice of container and precautions:

• Low-binding sterile polypropylene to prevent absorption
• Borosilicate glass vials to prevent absorption in the glass walls
• Avoid polystyrene
• Avoid lab plastic containers 
• Avoid amber vials or opaque containers 

Overview of Retatrutide Peptide:

Retatrutide (LY3437943) is a triple hormone receptor agonist peptide. Research indicates that it is primarily designed to target metabolic disorders such as obesity and type 2 diabetes, as shown in preclinical models. ®

These types of receptor agonists are of growing interest in the field of metabolic and endocrinological research due to their multifaceted mechanisms of action. Scientific evidence suggests that further research is needed to explore its properties and roles as a receptor mediator in research subjects.

How Does The Peptide Work?

According to Lab research, it may simultaneously activate three receptors: GLP-1 (Glucagon-like peptide 1), GIP (Glucose-dependent insulinotropic polypeptide), and Glucagon receptors. ®

Lab experiments reveal that by interacting with GIP, GLP-1, and glucagon receptors, it may influence research models related to: ®

• GLP-1 (Glucagon peptide 1)

• GIP (Glucose-dependent insulinotropic polypeptide)
• Glucagon 

Scientific evidence suggests that Retatrutide activates GLP-1 receptors to stimulate insulin secretion and promote the feeling of fullness. By targeting the GIP receptor, Retatrutide works to boost insulin secretion in reference to regulating glucose levels in the blood in experimental models. 

It also has the potential to activate the Glucagon receptor. As per research models, it enhances the hormones to utilize energy to help in breaking the accumulated fat and maintaining the glucose level.

Here are some common side effects of the compound observed in different research models.

• Headache 
• Dizziness
• Fatigue
• Nausea
• Vomiting

TFA Salt Form 

Retatrutide is provided in its TFA salt form. Residual trifluoroacetate content typically up to –10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA.

Disclaimer

Retatrutide peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.

For queries, complaints, or support, please contact support@rcdbio.co.