Tirzepatide [Peptide]

Description

Tirzepatide [Peptide]

The product is only intended for laboratory research use and not for human consumption. 

Available quantities:

• 5 mg,
• 10 mg,
• 60 mg,

Product Information 

Product name	Tirzepatide
Peptide purity (HPLC)	98-99%
Molecular Formula	C225H348N48O68
Molecular Weight	4813 g/mol
Synonyms	Tirzepatida, Tirzepatidum, OYN3CCI6QE
CAS	2023788-19-2
Source	Synthetic
Form	Powder
Shelf Life	Up to 2 years in powder form under recommended conditions.

Molecular Sequence of Tirzepatide (LY3298176) Peptide 

H–Tyr–Aib–Glu–Gly–Thr–Phe–Thr–Ser–Asp–Tyr–Ser–Ile–Aib–Leu–Asp–Lys{γ-Glu–AEEA(2×OEG)–C20-diacid}–Ala–Phe–Val–Gln–Trp–Leu–Ile–Ala–Gly–Gly–Pro–Ser–Ser–Gly–Ala–Pro–Pro–Pro–Ser–NH₂ 

• “Aib” = α-aminoisobutyric acid (a non-natural amino acid).
• The Lys at position 20 is modified via a γ-glutamic acid (γ-Glu) linker plus two units of aminoethoxyethoxyacetic acid (AEEA, essentially 2×OEG) and a C20 fatty diacid moiety (eicosanedioic acid) attached to the ε-amine of that Lys. ® 
• The peptide backbone consists of 39 amino acids.

Handling and Storage of Tirzepatide (LY3298176)

The peptide compound should be stored in a cool and dry place to maximize its stability. Reconstituted liquid Tirzepatide should be stored at 2–8 °C for short-term storage.®

For Tirzepatide lyophilized peptides, it is recommended to store them in the refrigerator between 2°C and 8°C (36°F–46°F) in an air-sealed container. ®

Lab user exposure: 

• Avoid prolonged or repeated exposure.
• Avoid inhalation.
• Avoid contact with eyes or skin.
• The product is non-hazardous for lab-to-lab or air transportation.
• Handle inside standard laboratory containment.
• Use gloves, a lab coat, and protective eyewear.

Redissolving:

• Can be reconstituted in sterile distilled water or suitable buffer solutions.
• A small amount of DMSO or 0.1% TFA may be used to test or improve solubility.
• Mix gently, avoid high-temperature heating. 

Choice of container and precautions:

• Low-binding sterile polypropylene to prevent absorption
• Borosilicate glass vials to prevent absorption in the glass walls
• Avoid polystyrene
• Avoid lab plastic containers 

Overview of the Tirzepatide Peptide

Tirzepatide is a synthetic polypeptide dual agonist for GLP-1 and GIP. The peptide exhibits distinct characteristics from GLP-1 receptor agonists. ® Laboratory research indicates that Tirzepatide influences insulin release from the pancreas and decreases hyperglycemia in experimental models. 

Additionally, Tirzepatide (LY3298176) also has the potential to increase the level of adiponectin in laboratory models. ®

How Does The Peptide Work?

• Tirzepatide has shown potential glucose-lowering effects by activating GIP and GLP-1 synergy. Research focuses on its potential role of experimental compounds in type 2 diabetes (T2D) of experimental compounds. ®
• Preclinical experiments have shown promising results regarding the potential of Tirzepatide in weight management, particularly in individuals with a body mass index (BMI) of ≥ 30 kg/m² in experimental models. ®
• Several scientific studies have explored broader aspects of metabolic health involving Tirzepatide. Topics under investigation may include hypertension, dyslipidemia, and cardiovascular health markers in laboratory settings. ®

Besides potential mechanisms, here are some common side effects of the compound observed in different research models.

• Headache 
• Dizziness
• Fatigue
• Abdominal discomfort 

TFA Salt Form 

Tirzepatide peptide is provided in its TFA salt form. Residual trifluoroacetate content is typically up to 10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA.

Disclaimer

Tirzepatide peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.

For queries, complaints, or support, please contact support@rcdbio.co.