Table of Contents
Introduction
AC-262 356, also referred to as AC 262, is an advanced non-steroidal selective androgen receptor modulator (SARM) with promising implications. In a recent study conducted on castrated male rats over a 2-week duration, AC-262 356 exhibited remarkable potential in enhancing anabolic parameters. Particularly, it demonstrated significant efficacy in promoting the growth of the levator ani muscle and effectively suppressing elevated levels of luteinizing hormones. These findings highlight the notable impact of AC-262 356 as a performance-enhancing substance in animal models.
Although AC 262 356 could belong to a high class of muscle androgen receptors, it is still classified as a research chemical. This compound is unsafe for human consumption and should be purchased for research purposes only.
What is AC 262 356 Powder?
AC 262 356 powder is a selective androgen receptor modulator (SARM) that has gained attention in the realm of muscle growth and development. Selective androgen receptor modulators are compounds that selectively bind to and activate the androgen receptor in specific tissues, such as skeletal muscle, while minimizing the activation of the receptor in other tissues, such as the prostate gland.
AC 262 356 has shown promise in promoting muscle growth and increasing muscle mass. It exerts its effects by specifically targeting and activating androgen receptors in skeletal muscle cells, leading to enhanced protein synthesis and muscle hypertrophy. This selective action is crucial in avoiding potential side effects commonly associated with androgens, such as human cancer cells.
By activating the androgen receptor in skeletal muscle cells, AC 262 356 facilitates the development of lean muscle mass. It promotes the synthesis of new proteins, contributing to muscle repair and growth. Unlike traditional androgenic compounds, AC 262 356 is designed to minimize unwanted androgenic effects, making it an attractive option for research subjects seeking to enhance their physique.
Key Features
- 98% Purity
- 500mg | 1000mg
- Sold for research purposes only
- CAS Number 870888-46-3
- Molar Mass 278.355 g·mol−1
- Chemical Formula C18H18N2O
- IUPAC Name 4-[(1R,3S,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
How Does It Work?
AC-262 operates by mimicking the actions of testosterone, albeit with a more selective approach. Instead of binding to androgen receptors throughout the body, AC-262 primarily targets specific androgen receptors found in bone and muscle tissues. Notably, it exhibits minimal binding affinity to the prostate gland, setting it apart from testosterone’s widespread effects.
Supporting evidence from a 2-week chronic study in castrated male rats confirms this distinctive mechanism. Typically, androgen administration in castrated rats results in significant prostate and seminal vesicle enlargement. However, the study revealed that while testosterone caused a remarkable 10-fold increase in prostate size, AC-262 demonstrated weak effects on prostate enlargement.
Similarly, testosterone treatment led to a substantial 14-fold increase in seminal vesicle size compared to vehicle-treated castrated rats. In contrast, the administration of AC-262 at a dose of 3mg/kg only exerted a marginal effect on seminal vesicle size. Even at its highest dose, the increase in seminal vesicles was a mere 29.9±2.2% relative to testosterone treatment.
It is worth noting that despite its modest impact on prostate and seminal vesicle size, AC-262 still exhibited favorable effects on endocrine and anabolic parameters. In fact, it reached 117% and 66% of the maximum effects observed with testosterone for these parameters, respectively. Consequently, AC-262 demonstrates remarkable tissue-selectivity properties with minimal androgenic liabilities and adverse effects.
Potential Benefits of AC 262 356
AC-262 and Luteinizing Hormone
Luteinizing hormone, secreted by the pituitary gland, plays a crucial role in sexual development in both males and females. Elevated levels of LH beyond the normal range can lead to various issues such as infertility in females, reduced libido in males, and early or delayed puberty in children. [R]
In the aforementioned 2-week study, AC-262 effectively suppressed the castration-induced elevation of plasma LH levels. At a dose of 3mg/kg, AC-262 significantly decreased LH levels by 40%. Moreover, at higher doses of 10 and 30mg/kg, AC-262 demonstrated even stronger effects in suppressing LH compared to testosterone. [R]
AC-262 and Muscle Mass
A notable 2-week study conducted on castrated male rats demonstrated the robust anabolic effects of AC-262 on muscle weight. The administration of AC-262 led to a substantial restoration of the weight of the levator ani muscle, reaching approximately 70% of the maximum effect observed with testosterone (T). It is important to note that the maximum effects induced by AC-262 in these tissues were relatively lower compared to those induced by T. [R]
These findings highlight the potential of AC-262 as a novel selective androgen receptor modulator (SARM) with beneficial anabolic effects on muscle growth. [R]
AC-262 and Alzheimer’s Disease
In a rat study, AC-262 exhibited promising therapeutic potential for age-related cognitive decline and Alzheimer’s disease. This SARM up-regulated androgen receptor levels in the brain following castration, indicating its ability to modulate androgen signaling. Additionally, AC-262 antagonized impairments in higher spatial memory retention specifically in female mice. These findings suggest that SARMs, including AC-262, have the potential to counteract cognitive deficits in a mouse model of Alzheimer’s disease. [R]
In summary, animal studies have provided valuable insights into the effects of AC-262. The compound has shown significant anabolic effects on muscle growth, effectively suppressed LH levels, and displayed therapeutic potential for age-related cognitive decline and Alzheimer’s disease in animal models.
Further research is necessary to fully understand the effects and potential applications of AC-262 in humans.
Precautions to Consider
AC-262, being a non-steroidal compound with anabolic action, has shown promising results in studies conducted on animal models, particularly in terms of significant suppression of luteinizing hormone levels and increased muscle growth. However, it is important to note that AC-262 falls under the category of research chemicals and has not been extensively studied in humans.
Due to the limited research conducted on AC-262 and its potential effects on reproductive tissues, caution should be exercised. Individuals who have concerns regarding their reproductive health or those who are seeking to preserve fertility should avoid using AC-262 until further studies are conducted to assess its impact on reproductive tissues.
Potential Side Effects
As AC-262 is a research chemical with limited human studies, its safety and side effects profile is not fully understood. However, based on available information, it is important to consider potential risks and exercise caution when using AC-262. Some individuals may experience adverse effects such as hormonal imbalances, mood changes, or alterations in lipid profiles. Additionally, since AC-262 is a non-steroidal compound with anabolic properties, there is a possibility of unknown long-term effects on various body systems.
Conclusion
In conclusion, the use of AC-262, a non-steroidal androgen receptor modulator, offers several potential benefits. AC-262 selectively targets the body’s androgen receptors, focusing primarily on skeletal muscles while sparing the reproductive tissues. This specificity reduces the risk of prostate cancer development, a concern associated with some anabolic steroids. AC-262 has demonstrated an ability to increase muscle mass, promote higher spatial memory, and potentially aid in fat loss.
Furthermore, AC-262 has shown a favorable safety profile with limited effects on liver enzymes and natural testosterone production.
Although AC-262’s benefits are supported by animal studies and anecdotal evidence, its efficacy and safety in human trials remain to be fully established. However, as a research chemical with high purity and a non-steroidal nature, AC-262 represents a promising potential treatment for individuals seeking to enhance their performance and endurance levels while minimizing the risks associated with traditional anabolic steroids.
Further research is needed to elucidate the molecular changes and long-term effects of AC-262, as well as to explore its potential as a safer alternative to other SARMs and anabolic regulators.
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