Table of Contents
Introduction
Forskohlii root, scientifically known as Coleus Forskohlii (sometimes referred to as Coleus Forskolii), is an Ayurvedic medicinal herb that has been revered for centuries in Indian and Southeast Asian cultures. This plant, belonging to the mint family, is indigenous to India, Nepal, and Thailand.
In recent years, Forskohlii root powder has gained popularity in the Western world. The key active component found in the root is called Forskolin. This powder has been utilized for various medicinal purposes.
Researchers are currently conducting studies on a dietary supplement derived from Coleus Forskohlii extract to investigate its potential in fat burning. This research aims to address weight gain issues prevalent among the obese population.
Manufacturers typically offer gluten-free and non-GMO Coleus Forskohlii for sale, which is typically encapsulated in a gelatin capsule. This research chemical is often marketed as a compound that could help specific individuals achieve their weight-loss goals from the start.
Non-GMO Coleus Forskohlii is not an FDA-approved supplement, however, buy Coleus Forskohlii Extract compound for research purposes alone.
What is Coleus Forskohlii Extract?
Coleus Forskohlii, an herb deeply rooted in Ayurveda (Ayurvedic medicine), has garnered attention for its potential effects on the human body.
Current studies are focusing on Coleus Forskohlii extract as a possible fat-burning supplement. One of its primary bioactive ingredients is Forskolin. Supplementation with Coleus Forskohlii, rich in Forskolin, has shown potential in increasing testosterone levels, as well as providing protective effects against cancer and inflammation. This is believed to be attributed to Forskolin’s ability to elevate the concentration of cyclic adenosine monophosphate (cAMP), a crucial molecule in the body.
Higher cAMP levels are associated with accelerated fat loss, serving powerful effects on other fat-burning compounds. However, it is important to note that Forskolin is predominantly used as a research tool in vitro studies, such as in test tubes or Petri dishes. Thus, further research is required to validate these effects in the context of the human body.
Key Features
- 98% Purity
- 120mg/125ct/15g
- Sold for research purposes only
- CAS Number 66428-89-5
- Molar Mass 410.507 g·mol−1
- Chemical Formula C22H34O7
- IUPAC Name (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate
How Does It Work?
Forskolin has been proposed to aid in weight loss by supporting the production of lipase and adenylate cyclase enzymes. These enzymes help release fatty acids from the body’s cells, which can then be utilized as a source of energy. The idea is that by burning fatty acids, fat can be reduced without adversely affecting lean muscle mass.
However, it is important to note that weight loss requires a calorie deficit, meaning that a person’s calorie intake must be lower than their calorie expenditure. This fundamental principle cannot be ignored.
Potential Benefits of Coleus Forskohlii Extract
Coleus Forskohlii and Weight Loss
Clinical trials conducted on overweight and obese men have indicated reductions in body fat percentage and fat mass, along with increases in lean body mass and serum-free testosterone levels. Early studies have also suggested positive effects on women’s body composition and weight loss. Additionally, Coleus Forskohlii extract has shown some potential as an appetite suppressant. [R]
Nevertheless, further research is necessary to validate these findings, assess long-term effects, and determine the optimal dosage and safety profile of Coleus Forskohlii for weight management. [R]
Coleus Forskohlii and Eye Pressure
A study conducted in India investigated the use of 1% Forskolin eye drops and found a decrease in inner eye pressure in adults with open-angle glaucoma after four weeks of treatment. The study involved 90 test subjects aged between 18 and 60 with open-angle glaucoma and elevated intraocular pressure. Despite these promising results, additional research is necessary to validate the effectiveness and safety of Forskolin in managing eye pressure. [R] [R]
Coleus Forskohlii and Asthma Attacks
Forskolin has been found to inhibit the production of interleukins, eotaxin, and histamine, and it also exhibits antioxidant properties. A study involving 20 patients with asthma who were given 10 mg of oral Forskolin capsules daily for six months demonstrated positive control of asthma attacks. However, further laboratory trials are needed to explore the potential of Coleus Forskohlii in managing asthma symptoms and to determine its safety and efficacy. [R] [R]
Coleus Forskohlii Extract and Cardiovascular Health
Forskolin, a compound found in the extract, is believed to promote vasorelaxation, leading to the relaxation of smooth muscles in blood vessel walls. This mechanism increases the overall volume of the circulatory system while maintaining blood volume, potentially improving blood circulation, blood supply to internal organs, and myocardial efficiency. However, further research is required to fully understand and establish the cardiovascular benefits of Coleus Forskohlii. [R] [R]
Precautions to Consider
Test subjects with known allergies or sensitivities to herbs, plants, or any components present in Coleus Forskohlii should exercise caution and avoid using the extract. It is essential to carefully review the product’s ingredients and observe best practices for studying research chemicals when investigating the effects of Coleus Forskohlii.
Potential Side Effects
When Coleus Forskohlii extract is administered intravenously, test subjects may experience side effects such as flushing, rapid heartbeats, and low blood pressure. In the case of inhalation, it can lead to upper respiratory tract irritation, coughing, tremors, and restlessness. Some may also experience eye-stinging, enlargement of blood vessels in the eyes, and headaches.
Conclusion
In conclusion, Coleus Forskohlii extract, derived from the roots of the Plectranthus Barbatus plant, is a natural and powerful Ayurvedic herb that offers a range of potential benefits. With its ability to target fat cells and promote optimal absorption, Coleus Forskohlii extract has garnered attention as a valuable ingredient in weight management formulations.
The extract’s effectiveness in supporting weight loss goals and combating obesity has been the subject of scientific research and positive consumer reviews. It is formulated from GMP-compliant facilities to ensure quality and safety.
As a tropical plant that grows in water-rich environments, Coleus Forskohlii is carefully cultivated to provide a sustainable and reliable stock of this beneficial extract. Its use in Ayurvedic medicine dates back centuries, and now, it is gaining recognition worldwide as a natural solution for achieving weight management goals. Its potential to target fat cells and aid in optimal absorption makes it a valuable addition to dietary supplements and wellness routines.
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