Introduction

Tianeptine Sodium, a tricyclic antidepressant, is increasingly utilized in research settings for its unique properties and mechanisms of action. Unlike traditional antidepressants, Tianeptine enhances serotonin uptake in the brain, offering novel insights into mood regulation and neuroplasticity. Researchers are exploring its potential applications in treating depression, anxiety, and stress-related disorders, as well as its neuroprotective effects. Its distinctive pharmacological profile makes Tianeptine Sodium a valuable subject in psychopharmacological and neurobiological studies.

What is Tianeptine Sodium?

Tianeptine sodium, which differs from other tianeptine forms such as tianeptine sulfate, is a chemical compound frequently employed in scientific research. It exhibits unique pharmacokinetics, characterized by rapid onset but a relatively short duration of therapeutic effects, necessitating frequent administration. Tianeptine sodium’s unique mechanism of action on glutamate receptors has prompted research into its potential benefits. Its regulatory status varies by region, often due to concerns regarding misuse and dependency. Therefore, it is crucial to emphasize the significance of adhering to local guidelines when using this compound, which is intended for research purposes to clarify its potential beneficial effects

Key Features

RCD.Bio offers Tianeptine Sodium with the following specifications:

• A purity of 98%, verified by third-party laboratory testing.
• Available in various forms:
  • Tianeptine Sodium  Powder:  5000mg available in 5g and 10g powder.
  • Tianeptine Sodium Capsules: 100mg (20ct, 40ct, 80ct), 125mg (40ct, 60ct, 120ct), and 25mg (40ct, 80ct, 160ct).
  • Tianeptine Sodium Tablets: 100mg (30ct, 60ct, 100ct) and 30mg (100ct).
• CAS Number: 30123-17-2
• Molecular weight: 458.9 g/mol
• Chemical Formula: C21H24ClN2NaO4S
• Synonyms: Tianeptine monosodium salt , Stablon
• IUPAC Name: sodium;7-[(3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl)amino]heptanoate

How Does It Work?

Tianeptine, a unique antidepressant agent, stands apart from conventional treatments like tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs). It functions by stimulating the uptake of serotonin, a neurotransmitter associated with mood regulation, in the brain’s cortical and hippocampal regions, as well as in platelets. Unlike most antidepressants, Tianeptine’s activity primarily revolves around serotonergic mechanisms, without binding to specific serotonin receptor subtypes. Additionally, it does not directly impact dopamine-related processes or monoamine uptake, but it does elevate the levels of dopamine metabolites and extracellular dopamine concentrations. These pharmacodynamic properties contribute to its antidepressant and anxiolytic effects.[R]

Further, tianeptine’s antidepressant effects and exceptional clinical tolerance are a result of its unique neurobiological properties. Recent research emphasizes the role of glutamate in the mechanism of action of tianeptine, which is consistent with preclinical studies that emphasize glutamate’s crucial role in the altered neuroplasticity underlying depressive symptoms. A study examines the mechanism of action of tianeptine, focusing on its interaction with the glutamatergic system as a potentially important c action pathway. This convergence of evidence sheds new light on how tianeptine, by targeting the glutamatergic system, could be utilized in the potential treatment of depressive disorders.[R]

Potential Benefits of Tianeptine Sodium

Numerous research investigations and trials on animals suggest that Tianeptine Sodium may have a number of benefits.

Tianeptine Sodium on Depressive Relapse or Recurrence

In a study conducted on test subjects, the true promise of tianeptine shines through in its potential long-term effects. Over up to a year of tianeptine treatment, progressive therapeutic improvements have been observed. Moreover, it shows the potential to reduce the rate of relapse or recurrence, providing a glimmer of hope for those seeking sustained relief from depression. Importantly, tianeptine isn’t limited by age or post-alcohol withdrawal status, as it has shown potential in treating depression in elderly and post-alcohol withdrawal patient subgroups. This antidepressant’s unique chemical mechanism and ability to deliver long-lasting benefits make it a noteworthy contender in the quest to combat depression and enhance the quality of life for many individuals. [R]

Although the results are very promising. further research is required to determine the complete mechanisms underlying Tianeptines’s actions and to improve its application in major depression and Bipolar Disorder

Tianeptine and  Antidepressant Action

Tianeptine, an unconventional antidepressant commonly used in Europe for patients who do not respond well to selective serotonin reuptake inhibitors (SSRIs), has opened up new avenues for understanding potential depression treatments. Recent discoveries have revealed that tianeptine acts as a mu-opioid receptor (MOR) agonist, challenging traditional monoamine-based hypotheses of depression treatment. Research is focused on unraveling the neural circuits responsible for tianeptine’s potential antidepressant effects. Importantly, studies have shown that tianeptine can induce rapid antidepressant-like effects in mice with as little as one week of treatment. What sets tianeptine apart is its mechanism of action, which differs from traditional antidepressants in two key ways: (1) it relies on MORs for its enduring antidepressant-like effect, unlike other chemicals, and (2) it does not stimulate the generation of new neurons in the hippocampus, in contrast to a known antidepressant drug.[R]  However, it is important to note that Tianeptine Sodium is strictly intended for research use only.

Tianeptine Sodium and  Anti-nociceptive (Pain-Relieving) 

In a study evaluating the anti-nociceptive (pain-relieving) effects of tianeptine, it was discovered that male mice exhibited significant pain-relieving properties. When administered at doses inducing similar anti-nociception, tianeptine demonstrated effectiveness in reducing pain, underscoring its potential to alleviate discomfort. This highlights tianeptine’s capacity to provide pain relief, a quality that could be explored further in the context of pain management strategies. However, it’s crucial to emphasize that the study’s focus was on tianeptine’s anti-nociceptive effects on mice, Further research is needed to explore the full therapeutic potential of Tianeptine Sodium [R]

Precautions to Consider

When researching Tianeptine Sodium, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals

Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow the recommended dosage in the warning section

Adhere to the recommended dosage instructions outlined on the product label. Avoid a significant increase of the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential side effects 

Potential side effects of tianeptine may include drowsiness, confusion, difficulty breathing, coma, and death when taken in high doses. Long-term use of tianeptine can lead to dependence and withdrawal. Additionally, respiratory depression, a known side effect of opioids, may also be observed with tianeptine.  [R] [R]

Where Can I Buy  Tianeptine Sodium Online?

RCD.bio offers Tianeptine Sodium for laboratory and research use only.

When buying pure tianeptine Tianeptine Sodium, it is important to choose a reputable market seller who provides quality  Tianeptine Sodium. At RCD.bio, customers can ensure each product is accompanied with a third-party-issued Certificate of Analysis showing the identification, purity, and concentration of our product. Guaranteed faster day shipping by air worldwide including China.

RCD. Bio also offers Tianeptine Sodium quantity in various forms:

• Tianeptine Sodium  Powder:  5000mg available in 5g and 10g powder.
• Tianeptine Sodium Capsules: 100mg (20ct, 40ct, 80ct), 125mg (40ct, 60ct, 120ct), and 25mg (40ct, 80ct, 160ct).
• Tianeptine Sodium Tablets: 100mg (30ct, 60ct, 100ct) and 30mg (100ct).

RCD.Bio provides Tianeptine Sodium in three distinct forms to cater to various research requirements. The 5000mg powder form, available in 5g and 10g options, offers versatility but may pose taste challenges that could affect test subject compliance. In contrast, the capsule form provides precise dosage options with choices of 100mg (20ct, 40ct, 80ct), 125mg (40ct, 60ct, 120ct), and 25mg (40ct, 80ct, 160ct). Tablets, available in 100mg (30ct, 60ct, 100ct) and 30mg (100ct), present a tasteless and straightforward alternative, eliminating the need for preparation or measurement. Tablets not only ensure convenience but also enhance stability and shelf life, making them ideal for long-term research projects. Your choice among these forms should align with the specific demands of your research or experiment, ultimately aiding in selecting the most suitable form for your needs.

Conclusion

Tianeptine Sodium, a chemical compound used in scientific research, offers unique features for those exploring its potential. With a purity of 98% and available in various forms, it stands out as a promising avenue of study. Its mechanism of action primarily involves the stimulation of serotonin uptake, contributing to its antidepressant and anxiolytic effects. Additionally, Tianeptine’s interaction with the glutamatergic system opens doors to novel approaches in addressing depressive disorders.

This compound has shown promise in reducing depressive relapse rates and inducing rapid antidepressant-like effects. It also exhibits anti-nociceptive properties, making it a candidate for pain management strategies, and may enhance cognitive function like a nootropic. While its multifaceted pharmacology suggests diverse benefits, it’s essential to underscore that Tianeptine Sodium is strictly intended for research purposes. Further research is necessary to fully understand its mechanisms and therapeutic potential, but its unique properties offer valuable insights for future exploration and potential applications.

Disclaimer

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