Myo-Inositol Trispyrophosphate (ITPP) [Powder]

Description

Myo-Inositol Trispyrophosphate (ITPP) [Powder]

Preclinical studies have indicated that Myo-Inositol Trispyrophosphate (ITPP) is a synthetic derivative of myo-inositol. This compound is a modified form of inositol (C₆H₁₂O₆). It carries three attached pyrophosphate groups (–P₂O₇⁴⁻).

This results in a 1:3 stoichiometric ratio between the inositol core and its pyrophosphate substituents, generating a highly charged phosphorylated molecule. Therefore, the molecule exhibits distinct properties in laboratory research.

Within controlled experimental models, ITPP has been investigated for its potential role in modulating hypoxia-related pathways. For example, the pathways include tumor microenvironment, cardiovascular ischemia, and neurodegenerative disorders in laboratory research models.

What is the Mechanism of Action of Myo-Inositol Trispyrophosphate (ITPP) in Preclinical Research?

Research-based investigations in experimental models suggest that Myo-Inositol Trispyrophosphate (ITPP) works through several molecular pathways. These pathways help explain its mechanism of action. The following is a structured breakdown of how it works:

Allosteric Hemoglobin Modulation

Preclinical research has shown that ITPP functions as an allosteric effector of hemoglobin. It interacts with hemoglobin molecules and decreases their affinity for oxygen. Consequently, this facilitates oxygen release under controlled laboratory conditions.

Oxygen Dissociation Curve Shift

In experimental systems, ITPP has been observed to induce a rightward shift in the oxygen dissociation curve. This effect enhances oxygen unloading capacity, increasing oxygen availability within research models of hypoxia.

Hypoxia-Responsive Pathway Regulation

Laboratory studies suggest that ITPP may influence hypoxia-associated molecular pathways. These include pathways linked with cellular metabolism, angiogenesis regulation, and oxidative stress modulation. These effects are still under active investigation in experimental models.

What are the Potential Benefits of Myo-Inositol Trispyrophosphate?

• May be useful for studying hemoglobin allosteric regulation.
• May supports hypoxia and oxygen-release research models.
• Investigated in preclinical oncology studies exploring tumor oxygenation.
• Has been investigated for potential insights into neurovascular hypoxia in preclinical research models.

What are the Potential Side Effects of (ITPP)?

The following potential effects have been reported in some preclinical studies under specific conditions:

• May cause Oxidative stress in lab models 
• May cause Metabolic imbalance during laboratory experiments 
• May cause Inflammation in research models 
• May cause cellular damage in some laboratory conditions 
• Mitochondrial stress in selected preclinical models

Why choose RCDbio for Myo-Inositol Trispyrophosphate?

RCDbio provides research chemicals, laboratory-grade extracts, and peptides with third-party testing for quality and purity standards. We aim to be your trusted online source for this research-grade powder and other research-grade compounds. In addition, we provide a quick and secure transaction experience to our buyers.

FAQs

What is the suggested shelf life of Myo-Inositol Trispyrophosphate ITTP? 

The shelf life of ITPP is typically 2-3 years when stored under recommended conditions.

How does Myo-Inositol Trispyrophosphate ITPP decompose?

The decomposition process of ITPP mainly happens through hydrolytic cleavage of pyrophosphate groups. Direct sunlight, excessive heat, or moisture can speed up the instability. 

What are the recommended storage conditions for Myo-Inositol Trispyrophosphate ITPP?

It should be stored in a sealed container at –20 °C. Additionally, the powder should be protected from light and moisture. 

Is Myo-Inositol Trispyrophosphate ITPP soluble in water?

Yes. ITPP is soluble in sterile distilled water. The solubility of the compound depends on pH and the ion strength of the medium. 

Disclaimer

Myo-Inositol Trispyrophosphate is exclusively for laboratory research purposes. RCD bio products are not intended to diagnose, prevent, or cure any disease. By purchasing, you agree to our Terms and Conditions. In addition, RCDbio reserves the right to refuse sales to unauthorized individuals. 

For queries, complaints, or support, contact support@rcdbio.co.