What is Galantamine Hydrobromide Powder?
Galantamine is a reversible and competitive inhibitor of the enzyme acetylcholinesterase (AChE) and is approved for treating Alzheimer’s disease. It also acts as an allosteric modulator of nicotinic acetylcholine receptors (nAChR). By activating nAChR and increasing the expression of the anti-apoptotic protein Bcl-2, galantamine may help prevent apoptosis and provide neuroprotection.
Galantamine is a naturally occurring tertiary alkaloid and was first discovered and isolated from plant sources like Galanthus nivalis in the early 1950s. Initially, it was studied for its effects on neuropathic pain and paralytic conditions such as post-polio paralysis, myopathies, and neuromuscular blockade reversal.
The remarkable discovery of Galantamine’s ability to inhibit acetylcholinesterase led to its exploration as a potential treatment for various psychiatric disorders. However, due to the challenges associated with extracting and synthesizing Galantamine, its reemergence as a therapeutic option for Alzheimer’s disease didn’t occur until the early 1990s. In 2001, it received FDA approval for the treatment of Alzheimer’s disease, ranging from mild to severe cases.
| Product Type | Powder |
| Product Name | Galantamine Hydrobromide Powder |
| Application | Acetyl cholinesterase inhibitor |
| CAS | 357-70-0 |
| Molar Mass | 287.359 g·mol−1 |
| Chemical Formula | C17H21NO3 |
| IUPAC Name | (4aS,6R,8aS)-5,6,9,10,11,12-Hexahydro-3-methoxy-11-methyl-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol |
| Synonyms | Galantamine HBr |
| Storage | Minimize open-air exposure and store in a cool, dry place |
| Terms | Kindly ensure you understand the scientific applications of this product, and make sure to read the Terms and Conditions before making a purchase. By completing your order and making the payment, you agree to our Terms and Conditions. Please note that the packaging of the product might slightly differ from what is shown on the website. In case you are not 100% satisfied with the product you receive, you can contact us at support@rcdbio.co. We will be glad to help you, as customer satisfaction is our top priority. ATTENTION: All RCDbio products are strictly restricted to LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used on humans or animals. |
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Ordering process was easy and the powder quality is great.
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