What is Melanotan-1 Nasal Spray?
Melanotan-1 (also known as afamelanotide) is a synthetic analog of α-Melanocyte-stimulating hormone (α-MSH). According to researchers, MT1 (Melanotan 1) is designed to potentially enhance the skin’s natural pigmentation.
In various research subjects, MT1 has been shown to trigger melanin production, initiating melanogenesis in the epidermis. MT1 nasal spray is used to study its absorption and pharmacokinetics via the nasal mucosa.
Chemical Properties
Pubchem CID | 16164658 |
Molecular Formula | C78H111N21O19 |
Molecular Mass | 1646.8 g/mol |
Synonyms | Melanotan-I MT-I;[Nle4,D-Phe7]-α-MSH FM39599 |
How Does Melanotan-1 Nasal Spray Work?
Studies have shown that Melanotan-1 selectively binds to the MC1R, a G protein-coupled receptor located in melanocytes. After binding to this receptor, MT1 activates melanogenesis. Here is a quick breakdown of how MT1 works:
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Activation of Adenylate Cyclase
The receptor activation induces adenylate cyclase. Adenylate cyclase is an enzyme that may increase levels of cyclic AMP (cAMP) within the cell. It may also elevate cAMP, which then activates protein kinase A (PKA), a key enzyme in intracellular signaling.
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Transcriptional Activation
Activated PKA phosphorylates and activates CREB (cAMP response element-binding protein). CREB is a transcription factor that promotes the expression of pigmentation-related genes.
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Upregulation of Tyrosinase
After these actions, the amount of the expression of tyrosinase, the rate-limiting enzymes in melanin biosynthesis, increases. This ultimately helps accelerate the melanogenesis process.
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Absorption via Nasal Mucosa
Researchers have observed that when MT1 is absorbed through the nasal mucosa in experimental models, it bypasses first-pass metabolism. This shows that it offers quick effects with more rapid outcomes.
What are the Potential Benefits of Melanotan-1 Nasal Spray?
In certain controlled environments, MT1 nasal spray is being studied for the following potential benefits.
- Promotes melanin production in skin cell studies
- May enhance UV protection in experimental models
- Investigated for managing pigmentation disorders
- May support circadian rhythm-related pathways
- Shows potential antioxidant effects in research
What are the Potential Side Effects of Melanotan-1 Nasal Spray?
Researchers have also observed a few side effects of the MT1 nasal spray. However, long-term research is still necessary to fully understand the safety profile of this compound.
- Reduced receptor response in research settings
- Uneven pigmentation was observed in research subjects
- Elevated oxidative stress in some experimental models
- Off-target receptor activation in Research assays
- Cytotoxicity at high doses in cell-based studies
Where to Buy Melanotan-1 Nasal Spray?
There are various online shops that provide you with this nasal spray. However, getting Melanotan-1 nasal spray from Rcdbio.co will give you peace of mind that you are trusting the right sources.
Our Melanotan-1 nasal spray meets strict quality protocols and purity standards. It is suitable for use in advanced laboratory settings. In addition, each batch undergoes consistency and purity testing. We provide a proper certificate of analysis of this product as well. Additionally, we provide fast and efficient delivery to ensure researchers receive their materials promptly.
FAQs
1. What is the shelf life of Melanotan-1 nasal spray in research settings?
The shelf life of Melanotan-1 nasal spray is typically 12 to 24 months. However, this can vary based on formulation and packaging.
2. How should Melanotan-1 nasal spray be stored in experimental studies?
To maintain peptide stability and potency, you need to store it in a safe environment. Therefore, MT-1 nasal spray should be stored at 2–8°C (refrigerated) away from sunlight.
3. Is Melanotan-1 stable at room temperature during handling?
Short-term exposure to room temperature (up to 25°C) may be acceptable. However, prolonged storage at room temperature may lead to degradation and loss of activity.
4. What conditions accelerate the degradation of Melanotan-1 in research samples?
Exposure to high temperatures, light, and repeated freeze-thaw cycles may accelerate peptide degradation in experimental preparations.
Disclaimer:
Melanotan-1 is exclusively for laboratory research purposes. RCDbio.co products are not intended to diagnose, prevent, or cure any disease.
The Food and Drug Administration has not evaluated the statements on our website. Researchers must comply with all applicable local laws and regulations. By purchasing, you agree to our Terms and Conditions. In addition, RCDbio.co reserves the right to refuse sales to unauthorized individuals.
For queries, complaints, or support, contact support@rcdbio.co.
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