Thymosin Alpha 1 [Peptide]

Description

Thymosin Alpha 1 [Peptide]

The product is only intended for laboratory research use and not for human consumption. 

Available quantities:

• 5 mg
• 10 mg
• 20 mg
• 50 mg

Product Information 

Product Name	Thymosin Alpha 1 [Peptide]
Peptide purity (HPLC)	98-99%
Molecular Formula	C129H215N33O55
Molecular Weight	3108.3 g/mol
CAS	62304-98-7
IUPAC	Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-Gly-Arg-Glu-Ala-Pro-Ala-Asn-OH
Source	Synthetic
Form	Powder
Shelf Life	Up to 2 years in powder form under recommended conditions

Molecular Sequence of Thymosin Alpha 1 Peptide

H–Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn–OH

Ac-SDAVDTSEITTKDLKEKKEVVEEAEN-OH

Length: 28 amino acids

N-terminus: Acetylated (Ac-)
C-terminus: Free acid (-OH)

Handling and Storage of Thymosin Alpha 1 Peptide

The peptide compound should be stored in a cool and dry place to maximize its stability. For Thymosin Alpha-1 lyophilized peptides, it is recommended to store them in the refrigerator between 2°C and 8°C (36°F–46°F) in an airtight container. 

Lab user exposure: 

• Avoid prolonged or repeated exposure.
• Avoid inhalation.
• Avoid contact with eyes or skin.
• Handle inside standard laboratory containment.
• Use gloves, a lab coat, and protective eyewear.

Redissolving:

• Can be reconstituted in sterile distilled water or suitable buffer solutions.
• A small amount of DMSO or 0.1% TFA may be used to test or improve solubility.
• Mix gently, avoid high-temperature heating. 

Choice of container and precautions:

• Low-binding sterile polypropylene to prevent absorption
• Borosilicate glass vials to prevent absorption in the glass walls
• Avoid polystyrene
• Avoid lab plastic containers 

Overview of the Thymosin Alpha 1 Peptide

Thymosin Alpha-1 (Thymosin Alpha) is a synthetic peptide derived from a natural protein found in the thymus gland. Preclinical researches suggest that the compound plays a key role in immune regulation. It is studied for its potential immunomodulatory effects, including enhancing defense mechanisms by boosting the activity of T-cells and other immune responses in laboratory research models.

Working Mechanism of Thymosin Alpha 1 Peptide

• Preclinical studies suggest that Thymosin Alpha 1 peptide may bind to Toll-Like Receptor 2 (TLR2) and Toll-Like Receptor 9 (TLR9) on immune cells in experimental models. 
• Laboratory studies indicate that the compound may activate MyD88-dependent signalling pathways.
•  It may trigger downstream activation of NF-κB and AP-1 transcription factors and may modulate immune production cytokines L-2, IL-6, IL-12, IFN-α and IFN-γ, TNF-α (in controlled levels) in laboratory models. 

TFA Salt Form 

Thymosin Alpha-1 is provided in its TFA salt form. Residual trifluoroacetate content is typically up to 10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA. (R)

Disclaimer

Thymosin Alpha-1 peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.