FGL Peptide

Description

FGL Peptide

FGL is a 15-amino-acid-long synthetic peptide, a variant of the natural cell adhesion molecule (NCAM protein). In scientific studies, FGL stands for Fibroblast-Growth Factor-like Loop, commonly referred to as the FG-loop. 

Studies suggest that FGL peptide directly or indirectly interacts with fibroblast growth factor receptor-1 (FGFR1). This mechanism of the synthetic peptide affects signaling pathways that support cell survival and synaptic changes in laboratory settings.

Additionally, FGL peptide is being researched for its neurotrophic, neuroprotective, synaptic plasticity, and anti-inflammatory properties in experimental models. 

Chemical Properties 

Product Name	FGL peptide
CAS	499993-62-3
Molar Mass	1649.8 g/mol
Chemical Formula	C71H116N20O25
Synonyms	FGL peptide, HY-P3281, 499993-62-3, DA-53184, CS-0655069
IUPAC Name	H-Glu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala-OH

What is the Working Mechanism of FGL Peptide?

Research-based studies on experimental models have shown that the FGL-loop may act through multiple biological pathways. Here is a detailed breakdown of its working mechanism:

Potential for Intracellular Signaling

FGL peptide has the ability to activate growth signaling pathways MAPK/ERK pathways. These signaling pathways transmit messages to neurons to connect with other neurons and make essential proteins required for focus and memory in experimental models. 

Activation of PI3K/Akt Pathway

This signaling mechanism of FGL peptide potentially helps in keeping the neurons safe through the process of apoptosis, cell repair, and cellular energy regulation. 

Potential to Improve Memory Under Laboratory Settings 

• The synthetic peptide, by attaching to (FGFR 1) receptor, turns on genes inside the cell nucleus to make specific proteins used for memory and learning in research models
  
• These proteins may include BDNF (Brain-Derived Neurotrophic Factor), CREB (cAMP Response Element Binding protein), Synapsin, and GAP-43.
• In addition to the above, FGL also protects neurons from oxidative stress, toxins, and lack of oxygen by turning on protective pathways such as Akt/mTOR. 

What Are the Potential Research Benefits of FGL Peptide?

In various laboratory settings, the following benefits of the synthetic researched peptide have been observed:

• It may support cognitive function in research models.
• It may promote neurogenesis in research subjects.
• It may reduce neuroinflammation in research models.
• It may enhance neuronal survival in research subjects.
• It may strengthen synaptic connections in research models.

What Are Potential Side Effects of FGL Peptide?

Researchers have observed the following side effects under laboratory conditions:

• Temporary fatigue 
• Mood fluctuations 
• Mild headaches 
• Insomnia 
• Mental overstimulation

Why Buy FGL Peptide From RCDbio?

RCDbio provides research-grade peptides intended solely for laboratory research purposes. RCDbio aims to be your trusted online source for research-grade synthetic compounds. 

All our products are supported by a Certificate of Analysis (COA). In addition, we provide a quick and secure transactional experience to our buyers.

FAQs

What are the optimal storage conditions for FGL Peptide?

The optimal storage recommendation is to store in a cool and dry place at −20 °C. Keep it protected from direct sunlight and moisture.

In what form does FGL peptide come in?

These peptides typically come as a freeze-dried powder (lyophilized form). It is easy for researchers to mix the peptide powder in different solutions for laboratory experiments. 

Is FGL peptide approved for medical use in the USA?

No, the peptide powder is not yet approved by the FDA and is only available for clinical research purposes. So, these peptide powders remain an investigational compound.

How should peptide powders be handled?

These compounds should be handled under controlled laboratory conditions, following standard laboratory safety protocols. 

Disclaimer

FGL peptide powder formulations are intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.

For queries, complaints, or support, please contact support@rcdbio.co.