Copper Peptide GHK-Cu 2:1 [Peptide]

Description

Copper Peptide GHK-Cu 2:1 [Peptide]

The product is only intended for laboratory research use and not for human consumption. 

Available quantities:

• 2 mg
• 5mg
• 10mg
• 50mg
• 100mg
• 500mg
• 1000mg

Product Information 

Molecular Sequence of Copper Peptide GHK-Cu 2:1 [Peptide]

Gly–His–Lys
Or in full N- to C-terminus notation:
H–Gly–His–Lys–OH

• Gly = Glycine
• His = Histidine (primary copper-binding residue)
• Lys = Lysine
• OH = Free C-terminal carboxyl group

Handling and Storage of Copper Peptide GHK-Cu 2:1 [Peptide] 

The peptide compound should be stored in a cool and dry place to maximize its stability. For better storage, it is recommended to keep the Copper Peptide GHK-Cu 2:1 lyophilized peptides refrigerated between 2°C and 8°C (36°F–46°F) in an air-sealed container.

Overview of Product

Preclinical studies have indicated that Copper Peptide GHK-Cu 2:1 is a combination of naturally occurring peptides Glycyl-L-Histidyl-L-Lysine (GHK) and copper ions.

In laboratory peptide research, the term 2:1 refers to the molar ratio that includes two molecules of GHK that bind to one copper ion, forming a stable peptide-copper complex. In preclinical studies, it has been detected in plasma, saliva, and urine of research models. 

Working Mechanism of Copper Peptide GHK-Cu 2:1

• In cell culture studies, GHK-Cu 2:1 has been shown to increase the activity of copper-dependent enzymes in experimental models. In addition, GHK-Cu 2:1 was found to act as a copper ion carrier in laboratory models. 
• Lab evidence revealed that GHK-Cu 2:1 caused an increase in extracellular matrix (ECM) protein expression and reduced pro-inflammatory cytokine expression.
• In a few experimental models, GHK-Cu 2:1 was found to influence the expression of various genes involved in inflammation, extracellular matrix production, and oxidative stress response. 

• In experimental peptide research, GHK-Cu 2:1 has been observed to stimulate vascular endothelial growth factor (VEGF) expression, promoting angiogenesis in tissue-engineered constructs.

Along with potential mechanisms, the compound also has some laboratory observations in preclinical settings:

• Cell stress
• Gene changes
• Slow growth
• Protein imbalance
• Cell shrinkage
• Variability observed in laboratory experiments

TFA Salt Form 

Copper Peptide GHK-Cu 2:1 is provided in its TFA salt form. Residual trifluoroacetate content is typically up to 10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA.
Disclaimer

Copper Peptide GHK-Cu 2:1 peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions.

For queries, complaints, or support, please contact support@rcdbio.co.