Piperine 98% [Tablets]

Description

What are Piperine 98% Tablets?

Piperine 98% tablets are research-grade formulations that contain approximately 98% pure piperine. Pure piperine is the bioactive compound found in black pepper (Piper nigrum). Researchers study piperine 98% tablets to learn how it improves the effectiveness of various drugs. [1]

The compound is also researched for its potential anti-inflammatory, antihypertensive, and hepatoprotective properties. [2] Researchers also study piperine 98% to understand its role in hepatic microsomes and Enterocytes. 

Chemical Properties

How Does Piperine 98% Tablets Work?

Piperine 98% has been shown to work in different ways in various research subjects. Here is how the compound works:

• Inhibition of Metabolic Enzymes

Researchers have observed that piperine may work by blocking the two enzymes, cytochrome P450 (CYP3A4) and UDP-glucuronosyltransferases (UGTs). These are the two most important enzymes as they potentially metabolize xenobiotics in research subjects.

Piperine reduces the first-pass metabolism of co-administered compounds by decreasing the activity of these enzymes. 

• Modulation of Efflux Transporters

In the studies of intestinal epithelium, Piperine has been shown to reduce P-glycoprotein (P-gp). P-gp is an efflux transporter that pumps drugs back into the intestinal lumen [2]. When this transporter is blocked, it increases the intracellular retention and translocation of active compounds across the intestinal barrier.

What are the Potential Benefits of Piperine 98% Tablets?

Researchers study piperine 98% tablets for the following potential benefits, in certain controlled environments.

• Enhances bioavailability in research subjects.
• Inhibits CYP3A4 enzyme activity in research settings.
• Suppresses P-glycoprotein efflux in research subjects.
• Reduces pro-inflammatory cytokines in research models.
• Boosts antioxidant enzyme levels in research settings.

What are the Potential Side Effects of Piperine 98% Tablets?

Researchers have also observed a few side effects of piperine 98% tablets. However, long-term research is still necessary to fully understand the safety profile of this compound. 

• Gastrointestinal disturbances in research subjects.
• Inhibition of hepatic enzyme clearance in research models.
• Altered xenobiotic metabolism in research settings.
• Potential drug-drug interactions in co-administration studies.
• Increases oxidative stress markers at high doses in research subjects

Where to Buy Piperine 98% Tablets? 

For authenticity, reliability, and purity, you can always trust RCDbio. You can buy piperine 98% tablets for research purposes from our online shop. We offer you third-party tested piperine 98% tablets at economical prices. 

In addition to that, we have a team of professionals who can always help you with your queries. We make sure you have a hassle-free shopping experience. Therefore, we give you a secure transaction option. 

FAQs

What is the half-life of Piperine 98% in Research Subjects?

The reported half-life of piperine in research subjects ranges from 1.0 to 2.5 hours. 

Does Piperine 98% Degrade? 

Yes, piperine is photosensitive and thermolabile. It can degrade under exposure to light, heat, and moisture, especially in non-stabilized formulations. 

What is the Best Temperature to Store Piperine 98%? 

Storing piperine 98% at a controlled room temperature between 2°C and 8°C is recommended. 

What is the Shelf Life of Piperine 98%? 

Under ideal storage conditions, the shelf life of piperine 98% is typically 24 months from the date of manufacture. However, its stability should be confirmed via periodic reanalysis.

What is the Toxicity of Piperine?

In research settings, piperine exhibits dose-dependent toxicity. Reported LD₅₀ values range from 330–400 mg/kg in research subjects.

Disclaimer:

Piperine 98% tablets are exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, prevent, or cure any disease. 

The Food and Drug Administration has not evaluated the statements on our website. Researchers must comply with all applicable local laws and regulations. By purchasing, you agree to our Terms and Conditions. In addition, RCDbio.co reserves the right to refuse sales to unauthorized individuals. 

For queries, complaints, or support, contact support@rcdbio.co. 

Reference Links

Piperine, Black Pepper (Piper nigrum). (n.d.). Restorative Medicine. https://restorativemedicine.org/library/monographs/piperine-black-pepper/

Tripathi, A. K., Ray, A. K., & Mishra, S. K. (2022). Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials. Beni-Suef University Journal of Basic and Applied Sciences, 11(1), 16. https://doi.org/10.1186/s43088-022-00196-1