Description
AICAR [Peptide]
AICAR is a short form of (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside). The peptide-like compound is also known as “Acadesine”, and is limited to laboratory studies. It is a naturally occurring molecule with the ability to act as an intermediate in the production of other nucleosides.
In laboratory studies, AICAR, a peptide-like compound, is researched for its potential ability to stimulate AMP-activated protein kinase (AMPK). It is a protein that has the potential to affect metabolic pathways.
Additionally, AICAR is a structural analog of adenosine monophosphate (AMP) studied for regulating cell energy, cell growth, cell repair, and metabolism in experimental models.
Chemical Properties
| Product Name | AICAR peptide |
| CAS | 2627-69-2 |
| Molar Mass | 258.23 g/mol |
| Chemical Formula | C9H14N4O5 |
| Synonyms | 5-Aminoimidazole-4-carboxamide ribonucleotide |
| IUPAC Name | N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide |
What is the Working Mechanism of AICAR Peptide?
Research-based studies on experimental models have shown that AICAR research peptides may act through multiple biological pathways. Here is a detailed breakdown of its working mechanism:
Stimulate AMPK
In laboratory models, AICAR-derived ZMP binds to the γ-subunit of AMPK. This mechanism leads to allosteric activation of AMPK that positively affects energy generation pathways and reduces energy consumption.
Effects on Muscle Endurance in Laboratory Models
AICAR-induced AMPK mimics the effects of exercise under laboratory conditions. By this mechanism, it may enhance resistance to fatigue, oxidative muscle fibers (Type I), and promote fatty acid oxidation instead of carbohydrate usage.
Influence Metabolic Pathways
According to scientific studies, this peptide-like compound has been hypothesized to improve insulin sensitivity and glucose uptake in laboratory models. This mechanism makes it a subject of research for interventions of metabolic dysregulation.
What Are the Potential Research Observations of AICAR Peptide?
While AICAR peptide is still under research, some areas of scientific interest include:
- May increase overall metabolic rate in experimental models.
- May improve cellular response to insulin in research models.
- May enhance the breakdown of fatty acids for energy under laboratory conditions.
- May increase glucose uptake by muscle cells in laboratory models.
What Are the Potential Side Effects of AICAR Peptide?
The following may be observed as side effects of the compound in research settings:
- Hypoglycemia
- Fatigue and headaches
- Cardiac effects
- Interference with cell growth
- Hypotension
Why Buy AICAR Compound From RCDbio?
RCDbio provides research-grade peptides intended solely for laboratory research purposes. RCDbio aims to be your trusted online source for research-grade synthetic compounds.
All our products are supported by a Certificate of Analysis (COA). In addition, we provide a quick and secure transactional experience to our buyers.
FAQs
What are the optimal storage conditions for AICAR Peptide?
The optimal storage recommendation is to store in a cool and dry place at −20 °C. Keep it protected from direct sunlight and moisture.
In what form does AICAR peptide come in?
These peptides typically come as a freeze-dried powder (lyophilized form). It is easy for researchers to mix the peptide powder in different solutions for laboratory experiments.
How should peptide powders be handled?
These compounds should be handled under controlled laboratory conditions, following standard laboratory safety protocols.
Disclaimer
AICAR peptide powder formulations are intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease.
The Food and Drug Administration has not evaluated the statements on our website. Researchers must comply with all applicable local laws and regulations. By purchasing, you agree to our Terms and Conditions.
For queries, complaints, or support, please contact support@rcdbio.co.
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Product works as expected.
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